Reduce NSAID toxicity with this

April 10th, 2012 at 5:15 am EST
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Hi Friend,

Hello and Good Morning to you and all of your significant others.

I hope you had an enjoyable Easter!

Pain killers, such as Metacam or Rimadyl can have a number of side effects, but if your dog is *really* in pain, then your dog might need to be taking them.

I prescribed these non steroidal anti-inflammatories (NSAID's) fairly often in practice ( while always encouraging alternate options)

Interestingly one study showed that you can lower the risk of intestinal damage ( which can lead to vomiting, diarrhea, ulcers), by using bovine colostrum.

Ultimate Canine Health Formula contains Bovine Colostrum, and if you have a dog on pain medication, it would be wise to also supplement with colostrum. You can get it here:

http://www.thedogsupplement.com



Here is some info from the study:


Co-administration of the health food supplement, bovine colostrum, reduces the acute non-steroidal anti-inflammatory drug-induced increase in intestinal permeability.
Clin Sci. 2001.

We therefore examined whether spray-dried, defatted colostrum could reduce the rise in gut permeability (a non-invasive marker of intestinal injury) caused by NSAIDs in volunteers and patients taking NSAIDs for clinical reasons.

Healthy male volunteers (n=7) participated in a randomized crossover trial comparing changes in gut permeability (lactulose/rhamnose ratios) before and after 5 days of 50 mg of indomethacin three times daily (tds) per oral with colostrum (125 ml, tds) or whey protein (control) co-administration.

A second study examined the effect of colostral and control solutions (125 ml, tds for 7 days) on gut permeability in patients (n=15) taking a substantial, regular dose of an NSAID for clinical reasons. For both studies, there was a 2 week washout period between treatment arms.

In volunteers, indomethacin caused a 3-fold increase in gut permeability in the control arm (lactulose/rhamnose ratio 0.36+/-0.07 prior to indomethacin and 1.17+/-0.25 on day 5, P<0.01), whereas no significant increase in permeability was seen when colostrum was co-administered.

In patients taking long-term NSAID treatment, initial permeability ratios were low (0.13+/-0.02), despite continuing on the drug, and permeability was not influenced by co-administration of test solutions. These studies provide preliminary evidence that bovine colostrum, which is already currently available as an over-the-counter preparation, may provide a novel approach to the prevention of NSAID-induced gastrointestinal damage in humans.

These studies provide preliminary evidence that bovine colostrum, which is already currently available as an over-the-counter preparation, may provide a novel approach to the prevention of NSAID-induced gastrointestinal damage in humans.

P.S. Will this help your dog for sure?

Nope.

Could it help your dog?

Yes

And it could also protect against NSAID side effects.

Alot of upside, and little downside.

At least supplement with colostrum, whether or not you use my formula.

But my supplement also contains nutrients for joint support AND colostrum in adequate and ACTIVE amounts to be helpful.

You can get a 50% TRIAL bottle here:

http://www.thedogsupplement.com

    


Heal Your Pets At Home!

Best Wishes,

Dr Andrew Jones

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DISCLAIMER: This information is for educational purposes only and is not intended to replace the advice of your own veterinarian. Dr Andrew Jones resigned from the College of Veterinarians of B.C. effective December 1 2010, meaning he cannot answer specific questions about your pet's medical issues or make specific medical recommendations for your pet.


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DISCLAIMER: This information is for educational purposes only and is not intended to replace the advice of your own veterinarian. Dr Andrew Jones resigned from the College of Veterinarians of B.C. effective December 1 2010, meaning he cannot answer specific questions about your pet's medical issues or make specific medical recommendations for your pet.

PRIVACY POLICY: We will never rent, sell, loan, provide, barter, exchange or in any way make available your personal information to others. You can unsubscribe or change your email address at anytime using the links at the bottom of this email.