CBD and Inflammation
Conventional Solutions to Arthritis and Joint Pain
NSAIDs
Non-steroidal anti-inflammatory drugs are what most people will get prescribed by conventional veterinarians who treat dogs with arthritis and joint pain. The problem....serious side effects.
Some of the most common NSAID’s prescribed by veterinarians are:
- carprofen (Novox or Rimadyl)
- deracoxib (Deramaxx)
- firocoxib (Previcox)
- meloxicam (Metacam )
When administering an NSAID, you should watch for these side effects:
- Decrease or increase in appetite
- Vomiting
- Change in bowel movements (such as diarrhea, or black, tarry, or bloody stools)
- Change in behavior (such as decreased or increased activity level, incoordination, seizure or aggression)
- Yellowing of gums, skin, or whites of the eyes (jaundice)
- Change in drinking habits (frequency, amount consumed)
- Change in urination habits (frequency, color, or smell)
- Change in skin (redness, scabs, or scratching)
- If you notice any of these possible side effects, stop the medication and contact your veterinarian
CBD (Cannabidiol) Research for Pain and Inflammation
Research overview
Research on CBD in animal models abounds and the cannabinoid seems to be able to interact with the immune system, reduce inflammation, and reduce pain from a number of conditions.
A 2015 review published in Bioorganic and Medicinal Chemistry discussed the anti-inflammatory properties of CBD. The reviewers found that CBD reduces inflammation through several pathways in the body, and represents an effective potential treatment for a range of conditions characterized by inflammation.
A 2016 study published in Clinical Hemorheology and Microcirculation investigated CBD as a treatment for early pancreatic inflammation in diabetic mice. Pancreatic inflammation can lead to diabetes due to an invasion of immune cells that destroy insulin-producing cells. The mice who received 10 weeks of treatment with CBD developed diabetes later than the mice that didn't receive the treatment. CBD-treated mice also showed a significant reduction in immune-cell activity.
A 2017 study in the journal Pain examined the effects of CBD in male rats with osteoarthritis. After two weeks, acute inflammation of the joints was reduced by local CBD treatment applied to the area. The administration of CBD was also found to prevent the development of nerve damage and joint pain.
Research using animal models has shown that CBD may be able to modulate the immune system. While CBD does not have much affinity for the body's cannabinoid receptors, it does affect other receptors and targets. According to a 2018 study published in Neurology, CBD binds to and desensitizes receptors known to mediate pain and sensory perception, inflammation, and body temperature.
How Full Spectrum Hemp Extract (CBD) for Dogs can help with Canine Arthritis
Full spectrum hemp extract (CBD) offers a wide variety of health-boosting benefits, with specific applications to help ease arthritis and the associated pain and mobility issues it can cause.
Pain Management
Full Spectrum Hemp extract can be very beneficial for reducing pain. Cannabis has been used as an effective analgesic dating back thousands of years. One of the ways it does this is actually by changing the way their central nervous system communicates the sensation of pain to our brains.
Inflammation
CBD and the other compounds found in a full spectrum hemp extract are known to reduce inflammation through the body. In many cases, the pain that our arthritic dogs feel is a direct result of the inflammation in their joints.
Immune – Modulation
CBD modulates our body’s immune responses. This is one of the main functions of the endocannabinoid system. Using the pathways of receptors in the endocannabinoid system, CBD increases communication between cells and allows them to function in a more efficient and proportional way.
In cases where arthritis is a result of an auto-immune response, like immune mediated polyarthritis, CBD can help by modulating the immune response
CBD Doses
Suggested starting doses are 1mg per 10lbs of body weight twice daily, up to 5mg/10lbs twice daily.
A minimum 4 week trial is suggested to see if this can be beneficial for your dogs or cats.
Few to no adverse effects are noted, even at the higher doses.
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