Hi Friend,
Cancer in our pets is the most feared diagnosis among pet owners. I myself worry about lumps on my pets, or the days when they seem more tired than normal.
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------------------------------------- Metronomic Chemotherapy -------------------------------------
Conventional treatment is often the only option when you are dealing with a serious, advancing type of cancer.
Cancers such as spleen tumors ( hemangiosarcoma), lymphatic tumors ( lymphosarcoma), or those linked with vaccine injections, fibrosarcoma.
Conventional treatment usually means high doses of very toxic drugs, chemotherapy.
But in certain situations, chemotherapy can be given at much lower doses, more frequently, and free of the more serious side effects.
Most chemotherapy drugs kill ALL fast-growing cells in the body, including white blood cells, hair and intestinal cells.
Metronomic chemotherapy works differently in that the drugs remove the blood supply to the tumor, leaving healthy cells untouched, but stopping the cancer from growing.
It may not eliminate the tumor, and in fact traditional chemotherapy seldom does that with our pets, but it puts the cancer into a remission giving your pet a quality of life.
Big advantages of this type of chemotherapy is that is us less expensive, easier to give in practice, and comes with little to no side effects.
Here is some more specific information from veterinarycancer.com
-------------------------------------- Veterinary Studies --------------------------------------
In veterinary medicine, there have been several studies published that give promise to the principle of metronomic or anti-angiogenic therapy. In dogs with incompletely resected soft tissue sarcomas, Elmslie, et al. [J Vet Intern Med 2008;22(6):1373-9)]showed that the use of low dose daily cyclophosphamide (cytoxan) and piroxicam (feldene) extended the time to recurrence over patients treated with surgery alone. In addition, Lana, et al. [J Vet Intern Med 2007;21(4):764-9]showed that in patients with hemangiosarcoma, the use of metronomic chemotherapy was associated with survival times equal to that of MTD chemotherapy.
Dr. Robert Kerbel (Toronto, Ontario) is one of the leaders in anti-angiogenic and metronomic therapy. He has recently suggested that the clinical benefit and impact could be greater if the therapy were initiated at earlier stages of malignancy. Therefore, at the Animal Cancer and Imaging Center, we recommend standard MTD chemotherapy combined with low dose metronomic therapy for many tumor types such as osteosarcoma and hemangiosarcoma. For other tumor types, metronomic chemotherapy may be the primary modality of therapy or will start after standard therapy has ended. We will discuss with you in detail what is the optimum use of this therapy for your pet as your pet’s individual condition and general health other than the cancer may have a impact on the schedule of treatment we utilize. It must be kept in mind that the laboratory and clinical research with metronomic chemotherapy administration is ongoing but extremely promising.
P.S. Discuss this with your veterinarian if your pet is diagnosed with cancer. I was not aware of it while in practice, but I would have considered it for many patients.
P.P.S. My book contains elaborate information on holistic cancer options. A great resource to have, and it costs less than most veterinary exams.
http:/www.veterinarysecretsrevealed.com
Heal Your Pets At Home!
Best Wishes,
Dr Andrew Jones
DISCLAIMER: This information is for educational purposes only and is not intended to replace the advice of your own veterinarian. Dr Andrew Jones resigned from the College of Veterinarians of B.C. effective December 1 2010, meaning he cannot answer specific questions about your pet's medical issues or make specific medical recommendations for your pet.
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