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Hello Friend,
Welcome to Wednesday.
I hope that you, and all of your family...dogs/cats/other critters and the other humans are doing well...
The current Coronavirus pandemic is difficult to fathom..and so disturbing with nearly 1.5 million cases worldwide, 81,000 deaths, 400,000 cases in the U.S., with 13,000 people dying..
There is a rash of current research, working on an array of treatments at different stages of the disease, as well as over 50 vaccine trials.
One in Washington State is now in human trials, planning on being able to vaccinate health care workers this fall.
There are hundreds of trials occurring around the world for new/re-purposed drugs to help..
But this takes time.
And in the interim many of you are facing immediate financial hardship-losing jobs, businesses closing.
It can be difficult to get to a veterinarian, or even afford one..
In light of this, we have decided to offer my membership site, Dr Jones' Inner Circle, all for Free.
Everying I have ever published... all the videos.. my Bestselling Book 'Veterinary Secrets: Natural Health for Dogs and Cats..My Getting Started with Veterinary Home Remedies Course..
You can get it for Free, No Credit Card or ongoing requirement....just your name and email:
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| Veterinary Parasite Drug Shows Early Promise Against COVID-19Source: WebMD
An inexpensive drug used to treat parasitic infections killed the coronavirus that causes COVID-19 in less than 48 hours in a laboratory setting, Australian researchers say.
The drug, ivermectin, has been used widely used for decades. It was introduced as a veterinary drug in the 1970s. Doctors also prescribe it to treat head lice, scabies, and other infections caused by parasites. According to a report published online in the journal Antiviral Research, the drug quickly prevented replication of SARS-CoV-2, the virus that causes COVID-19. The study has been peer-reviewed and accepted for publication, although it is not yet a "definitive" version of record.
Researchers infected cells with SARS-CoV-2, then exposed them to ivermectin. "We showed that a single dose of ivermectin could kill COVID-19 in a petri dish within 48 hours, indicating potent antiviral activity," says study co-author David Jans, PhD, a professor of biochemistry and molecular biology at Monash University in Melbourne.
Even at 24 hours, "there was a really significant reduction" in the virus, study leader Kylie Wagstaff, PhD, a senior research fellow in biochemistry and molecular biology at Monash University, said in a statement.
But experts say more testing is needed to know if it works well in people and if it’s safe to use.
"The main way we think ivermectin works is to target a key molecule of our cells that we think helps the virus to proliferate," Jans says. "By stopping this, the virus replicates more slowly, and so our immune system has a better chance to mount the antiviral response and kill the virus." Giving this or any antiviral drug early is thought to give the body the best chance of beating infection, he says.
In other studies, the researchers say, the drug has been shown to work against dengue fever and to limit infections similar to COVID-19, such as the West Nile virus.
The drug is "safe at relatively high doses, widely available, and relatively cheap, too," Jans says. The next step is more research to find the best dose for fighting COVID-19. Then researchers can begin testing in people, he says. "It is important to stress that no one should try to self-medicate with versions of ivermectin that are for veterinary purposes or head lice." The only safe way to get ivermectin is by prescription from a doctor, he says.
U.S. Experts Weigh In
The new study "certainly piqued our interest,” says Jill Weatherhead, MD, an assistant professor of adult and pediatric infectious diseases at Baylor College of Medicine in Houston. Her clinic uses the medicine to treat intestinal parasites found in international travelers or immigrants.
The important caveat, says Weatherhead, who reviewed the study but was not involved in the research, is that it was done in a lab. But "at this point, any lead we have should be investigated," she says. "What we really need to know is, could you translate that concentration [of the drug used in the lab study] into human studies and have it be safe?"
"The results are promising," agrees Katherine Seley-Radtke, PhD, a professor of chemistry and biochemistry at the University of Maryland, Baltimore County. She holds patents on compounds that are also being studied for COVID-19.
"Ivermectin," she says, "has shown effectiveness against other viruses, despite being an anti-parasitic drug." The drug is worthy of further study, Seley-Radtke says, but she calls the findings "very preliminary."
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| | Dr Jones Comments...
I have probably read about 50 different potential treatments for COVID, and from all I have read, I suspect this could be the most effective, short term treatment.
It is effective against most animal parasites, and has been widely used in veterinary medicine.. I may have treated myself a few times with it to 'rule out' any unwanted random critters..
It has proven effectiveness against other RNA viruses.
Obviously there is a big difference between petri-dish and real life, so there needs to be some preliminary testing.. Other potential options being researched that look promising include..
Convalescent plasma
Convalescent plasma from patients who have recovered from viral infections has been used as a treatment in previous virus outbreaks including SARS, avian influenza, and Ebola virus infection..https://www.washingtonpost.com/outlook/2020/04/07/plasma-recovered-patients-could-help-treat-covid-19-until-we-find-vaccine/
UBC-led study finds trial drug can significantly block early stages of COVID-19 in engineered human tissues.. https://www.med.ubc.ca/news/ubc-led-study-finds-trial-drug-can-significantly-block-early-stages-of-covid-19-in-engineered-human-tissues/
Colchicine Efficacy in COVID-19 Pneumonia.. https://clinicaltrials.gov/ct2/show/NCT04322565
Purine Repressing Probiotic Might Halt COVID-19, says Korean Researchers..https://geneonline.news/en/2020/03/21/purine-repressing-probiotic-might-halt-covid-19-says-korean-researchers/
Lactobacillus species in the gut microbiota have been found to block pro-inflammatory cytokines to inhibit harmful bacteria like Helicobacter pylori. While studying similar mechanisms against bladder inflammation (cystitis) causing E. coli, a team led by Professor Hana Yoon of Ewha Womans University Medical Center in Seoul, found abundant amounts of Lactobacillus gasseri present in the fermented extracts of sea buckthorn berries.
The probiotic has now been found to repress the activation of purine thereby preventing the SARS-CoV-2 from proliferating. Purine is an important compound required for nucleotide formation. Recent studies have found that the new coronavirus attacks purines in order to form its spike proteins and invade normal cells. The Korean team also found that the berries had several antioxidants, minerals, amino acids, and two other bacteria, Streptococcus thermophilus, and Lactobacillus rhamnosus that use the same binding site as that of SARS-CoV-2.
Montreal researchers propose treatment for COVID-19 https://www.macleans.ca/news/canada/a-made-in-canada-solution-to-the-coronavirus-outbreak/
Doctors Michel Chrétien and Majambu Mbikay, senior researchers at the Montreal Clinical Research Institute (IRCM), have proposed the use of a plant-based compound called quercetin to treat COVID-19. Clinical trials to test its effectiveness are scheduled to start in China within the next few weeks.
Chrétien and Mbikay say that quercetin, which some research suggests can protect against the Ebola and Zika viruses, may be able to treat the coronavirus. Working with Chinese health officials, they will supervise clinical trials for testing the drug on patients in China. They will use the drug produced by the Swiss company Quercegen Pharmaceuticals, which, according to Chrétien, produces the purest available quercetin. The trials will last around four months. |
| | I encourage you to look at my Inner Circle, and see all the array of alternative pet health information that can *really* help your dog or cat.
How You Can Help Us..
If you can…purchase something in the Dr Jones' Online Store- Ultimate Canine Health Formula, Ultimate Canine ADVANCED, Ultimate Feline, Ultimate CBD for Dogs and Cats, All the Digital and Hardcover Books, ALL the Videos, and every step by step Pet Healing Course.
Here's HOW to help your pet, Save 15%, and support our mission of providing Free, Holistic Dog and Cat Care Information to empower Pet Parents around the world
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| Heal Your Pet At Home!
Best Wishes,
Dr Andrew Jones, DVM |
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P.S. Take care of yourself and your family.
Stay well.
Avoid people.
But spend time with your pets. If you are to get COVID-19 it will be from humans.. NOT your dogs or cats..
I'll keep you updated as to any changes with COVID and how it could impact your dogs or cats.
Here is How you can help your dog or cat at home for Free:
P.P.S. Again, here are some of the benefits you'll receive from joining my Inner Circle for FREE..no credit card..ongoing requirement..just Good Karma :-)
Pet Food Diets, Recipes, and Advised Brands
Access to ALL of my current and past information in one place - my current YouTube Videos, Newsletters, Blog Posts and Podcasts.
Dr Jones' Getting Started with Home Remedies for Dogs and Cats Course
Pet First Aid Secrets, Online Edition - my Pet First Aid Manual, online
Previously Recorded Webinars and Teleseminars on multiple pet health topics
Dr Jones' Bestselling Book: Veterinary Secrets: Natural Health For Dogs and Cats
Huge Database of Previously Answered Questions - find answers right away!
Site Wide Search - search the entire site easily, find what you are looking for quickly and easily
Articles - previously written articles on alternative as well as conventional veterinary care... over THREE HUNDRED articles on current pet health and behavior issues
Hundreds of pages of pet health care content (TOO MUCH TO LIST HERE)
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| DISCLAIMER: This information is for educational purposes only and is not intended to replace the advice of your own veterinarian. Dr Andrew Jones resigned from the College of Veterinarians of B.C. effective December 1 2010, meaning he cannot answer specific questions about your pet's medical issues or make specific medical recommendations for your pet.
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