Some Japanese Knotweed published studies: _Fallopia japonica
Cancer
Fallopia japonica, a Natural Modulator, Can Overcome Multidrug Resistance in Cancer Cells.
https://www.ncbi.nlm.nih.gov/pubmed/26346937
Highest sources of useful secondary metabolites Resveritrol, Stilbenes and emodin found in Nature.
http://www.sciencedirect.com/science/article/pii/S0926669013003543
Production of medically valuable stilbenes and emodin in knotweed contained the greatest amounts of resveratrol, resveratroloside, piceid and emodin- an agent that could reduce the impact of type 2 diabetes. http://esciencenews.com/articles/2010/08/17/novel.diabetes.hope.comes.chinese.herbs
Lung disease COPD
Resveratrol and genistein may be potential drugs candidates for use in the treatment of COPD.
https://www.ncbi.nlm.nih.gov/pubmed/27035424
Research from Rensselaer Polytechnic Institute found that resveratrol has the ability to neutralize the toxic effects of proteins linked to Alzheimer's disease.
Caloric restriction and resveratrol promote longevity.
https://www.ncbi.nlm.nih.gov/pubmed/21364612
Bones
Resveratrol enhances exercise-induced cellular and functional adaptations of skeletal muscle in older men and women. https://www.ncbi.nlm.nih.gov/pubmed/28505227
https://www.ncbi.nlm.nih.gov/pubmed/20458604.
Breast Cancer
Resveratrol can be considered as a neo-adjuvant to improve sorafenib efficacy in breast cancer treatment. https://www.ncbi.nlm.nih.gov/pubmed/27863838
Blood vessels inflammation https://www.ncbi.nlm.nih.gov/pubmed/28069066
Skin Cancer
bioactive antioxidaion, anti-tyrosinase, immune stimulation and anticancer agents.
https://www.ncbi.nlm.nih.gov/pubmed/25311751
Lung Cancer
A resveratrol derivative induces lung cancer cell death.
https://www.ncbi.nlm.nih.gov/pubmed/20048747
Leukemia
promotes immune responses in leukemic mice through enhancing phagocytosis of macrophage and natural killer cell activities in vivo. https://www.ncbi.nlm.nih.gov/pubmed/25792654
Heart
Oral resveratrol and calcium fructoborate supplementation has therapeutic value in subjects with stable angina pectoris. https://www.ncbi.nlm.nih.gov/pubmed/23153742
Stress
"Antidepressant-like effect of trans-resveratrol in chronic stress model"
https://www.ncbi.nlm.nih.gov/pubmed/23174668
FAT
A study on the effect of resveratrol on lipid metabolism in hyperlipidemic mice.
https://www.ncbi.nlm.nih.gov/pubmed/24653579
Resveratrol might be a promising therapeutic treatment for obesity-related osteoarthritis.
https://www.ncbi.nlm.nih.gov/pubmed/28250578
DIABETES
Resveratrol improves insulin sensitivity, reduces oxidative stress and activates the Akt pathway in type 2 diabetic patients. https://www.ncbi.nlm.nih.gov/pubmed/21385509
Resveratrol inhibits cellular oxidative stress in monocytes cultured from type 1 diabetic patients
https://www.ncbi.nlm.nih.gov/pubmed/21813271
Alcohol
Resveratrol protects against alcohol-induced oxidative DNA damage in human peripheral lymphocytes.
https://www.ncbi.nlm.nih.gov/pubmed/21281738
Liver Cancer
Resveratrol-4-O-D-(2'-galloyl)-glucopyranoside isolated from Polygonum cuspidatum exhibits anti-hepatocellular carcinoma viability by inducing apoptosis via the JNK and ERK pathway.
https://www.ncbi.nlm.nih.gov/pubmed/24473215
https://www.ncbi.nlm.nih.gov/pubmed/19073162
Autism
Autism is associated with dysregulation of transcription factor signalling that can be corrected by resveratrol treatment in mice.
https://www.ncbi.nlm.nih.gov/pubmed/27578011
Brain protection
https://www.ncbi.nlm.nih.gov/pubmed/21221775
Colitis
Resveratrol may protect against colitis through up-regulation of SIRT1 in immune cells in the colon.
https://www.ncbi.nlm.nih.gov/pubmed/19940103
Spine injury & Brain Protection
https://www.ncbi.nlm.nih.gov/pubmed/21111721
Eyes
Resveratrol may prevent human senile cataract.
https://www.ncbi.nlm.nih.gov/pubmed/16500765
Anti-depressant
https://www.ncbi.nlm.nih.gov/pubmed/20353885
Resveratrol significantly reduced ovarian and adrenal androgens.
https://www.ncbi.nlm.nih.gov/pubmed/27754722
Prostate Cancer
https://www.ncbi.nlm.nih.gov/pubmed/19326431
Colon Cancer
Resveratrol suppresses colitis and colon cancer associated with colitis
https://www.ncbi.nlm.nih.gov/pubmed/20332304
https://www.ncbi.nlm.nih.gov/pubmed/20332304
Lung Cancer
https://www.ncbi.nlm.nih.gov/pubmed/20082145
Muscle Wasting
https://www.ncbi.nlm.nih.gov/pubmed/15477867
Muscular dystrophy
Coenzyme Q10 and resveratrol may have therapeutic value in muscular dystrophies.
https://www.ncbi.nlm.nih.gov/pubmed/21036052
Parkinson's disease
https://www.ncbi.nlm.nih.gov/pubmed/20167206
Alzheimer's disease
https://www.ncbi.nlm.nih.gov/pubmed/16951520
Chronic Pain
https://www.ncbi.nlm.nih.gov/pubmed/21308652
Osteoarthritis
https://www.ncbi.nlm.nih.gov/pubmed/21327438
Hypertension.
https://www.ncbi.nlm.nih.gov/pubmed/20671721
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